Keywords

• 88495-63-0 low price
• 88495-63-0 factory sells
• Artesunate Good Supplier In China

Quick Details

• ProName: 88495-63-0 low price 88495-63-0 facto...
• CasNo: 88495-63-0
• Molecular Formula: C19H28O8
• Appearance: Crystal white powder
• Application: Artesunate is an antimalarial agent. I...
• DeliveryTime: 3days
• PackAge: 1kg/pack
• Port: shanghai port
• ProductionCapacity: 100000 Kilogram/Year
• Purity: 99.5%
• Storage: dry and cool place
• Transportation: BY AIR,BY SEA
• LimitNum: 1 Kilogram
• Related Substances: qualified
• Residue on Ignition: qualifed
• Heavy Metal: qualified
• Valid Period: 2years
• Batch: 20210302

Superiority

88495-63-0 low price factory sells Artesunate Good Supplier In China

Artesunate is a derivative of artemisinin that is active against P. falciparum in vitro (IC₅₀ = 1.28 nM). It is an iron(II) oxide-reactive endoperoxide that generates reactive oxygen species (ROS) upon cleavage of its endoperoxide bridge. Artesunate inhibits proliferation of germinal center B cells in vitro and prevents development of arthritis via inhibition of germinal center formation and autoantibody production in the K/BxN mouse model of rheumatoid arthritis. It also inhibits alveolitis and pulmonary fibrosis induced by bleomycin  in rats.

Artesunate is a suppresses ROS-induced activation of the NLRP3 inflammasome. Arrests cell cycle in the G₂/M phase and sensitizes human renal cell carcinoma (RCC) cell lines to sorafenib in vitro. Antimalarial.

Details

Name

Artesunate

Synonyms

Molecular Structure

Molecular Formula

C19H28O8

Molecular Weight

384.43

CAS Number (Or Watson Number for Non-CAS Products)

88495-63-0

EINECS

Appearance

Specs/Standards

INP/Enterprise Standard

Use

Suitable for all kinds of cerebral malaria and severe malaria rescue