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Ms.NancyCAS NO.82854-37-3
99%(1-10000)Kilogram
Hot Sale 82854-37-3 reasonable price High Purity Echinacoside
Echinacoside is a caffeic acid derivative naturally found in plants, such as, Echinacea angustifolia DC. Echinacoside belongs to the class of phenylethanoid glycosides. In vitro studies have revealed the mode of action of echinacoside in breast cancer cells; echinacoside suppresses the Wnt/β-catenin signalling pathway exerting anticancer activity (Tang et al, 2020). Echinacoside has been reported as beneficial for human health in terms of neuroprotection, cardioprotectiony, anti-inflammatory, antioxidant and anti-osteoporotic activity
Echinacoside is a natural polyphenolic compound, has various kinds of pharmacological activities, such as anti-senescence, anti-hypoxia, anti-cancer, anti-osteoporosis, antioxidative, anti-inflammatory, neuroprotective, hepatoprotective, nitric oxide radical-scavenging and vasodilative ones. Echinacoside can improve the hematopoietic function of bone marrow in 5-FU-induced myelosuppression mice, it induces apoptotic cancer cell death by inhibiting the nucleotide pool sanitizing enzyme MTH1. Echinacoside inhibits cytochrome c release and caspase-3 activation caused by ensuing rotenone exposure via activating Trk-extracellular signal-regulated kinase (ERK) pathway in neuronal cells.
| Catalogue Number | E325620 |
| Chemical Name | Echinacoside Ethanolate |
| Synonyms | 2-(3,4-Dihydroxyphenyl)ethyl O-6-Deoxy-α-L-mannopyranosyl-(1→3)-O-[β-D-glucopyranosyl-(1→6)]-β-D-Glucopyranoside 4-[3-(3,4-dihydroxyphenyl)-2-propenoate] Ethanolate; |
| CAS Number | 82854-37-3 |
| Molecular Formula | C??H??O?? • x ( C?H?O) |
| Appearance | White to Off-White Solid |
| Melting Point | >150°C (dec.) |
| Molecular Weight | 786.73 + x(46.07) |
| Storage | Hygroscopic, Refrigerator, under inert atmosphere |
| Solubility | Methanol (Slightly), Water (Slightly) |
| Category | Standards; Pharmaceutical/API Drug Impurities/Metabolites; |
| Applications | Echinacoside Ethanolate is a caffeic acid glycoside, known for its neuroprotective, antiinflammatory and anti-oxidative activities. Also an anti[proliferative towards hypoxia influenced pulmonary artery smooth muscle cells. |