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CAS NO.721-50-6
99%(1-10000)Kilogram
Hot Sale 721-50-6 top purity 721-50-6 Prilocaine best quality
Prilocaine belongs to amide local anesthetic drug with its anesthesia intensity and speed being similar as lidocaine but with a longer duration period and weaker effect on vasodilation. It has a lower toxicity than lidocaine. It is clinically for local anesthesia, especially suitable for treating patients who are not allowed to use adrenaline.
[Pharmacological] its 3% solution has a similar local anesthesia efficacy as the anesthesia drug of 2% lidocaine together with adrenaline. It has a slow onset time which lasts about 6~7min and the duration time of about 1.5~2h. It has a strong penetration capability through mucous membranes. Adrenaline has a slightly prolonged duration of action. PPB is 55% and T1/2 of about 1.5h. It is subject to liver metabolism with its metabolites nitroso toluidine being able to oxidize hemoglobin to form methemoglobin. It can be transported to the fetus through the placenta.
Prilocaine is a local anesthetic of the amino amide type. Prilocaine is often used in dentistry. Prilocaine is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia.
Catalogue Number | P725005 |
Chemical Name | Prilocaine |
Synonyms | 2-(Propylamino)-o-propionotoluidide; (±)-N-(2-Propylaminopropionyl)-2-toluidine; (±)-Prilocaine; 2-Methyl-α-propylaminopropionanilide; Astra 1512; Astra 1515; Citanest; DL-(±)-Prilocaine; N-(2,6-Dimethylphenyl)-2-(propylamino)propanamide; NSC 40027; Prilocaine; Propitocaine; o-Methyl-2-propylaminopropionanilide |
CAS Number | 721-50-6 |
Molecular Formula | C??H??N?O |
Molecular Weight | 220.31 |
Category | Research Tools; |
Applications | Prilocaine is a local anesthetic of the amino amide type. Prilocaine is often used in dentistry. Prilocaine is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia. |