Shanghai Upbio Tech Co.,Ltd
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Ms.NancyCAS NO.657-24-9
99%(25-100)Kilogram
low price 657-24-9 trader Metformin Delivery
Metformin (Glucophage) was used in Europe for many years before it was approved for use in the United States in 1995. Metformin is the only approved biguanide for the treatment of patients with NIDDM that are refractory to dietary management alone. Metformin does not affect insulin secretion but requires the presence of insulin to be effective. The exact mechanism of metformin’s action is not clear, but it does decrease hepatic glucose production and increase peripheral glucose uptake. When used as monotherapy, metformin rarely causes hypoglycemia.
Inhibits hepatic gluconeogenesis by activating AMP-activated protein kinase (AMPK). A widely used anti-hyperglycemic (anti-diabetic) agent for the treatment of type 2 diabetes mellitus. Anti-cancer activity of metformin has been attributed to several mechanisms such as inhibition of mammalian target of rapamycin (mTOR), cancer stem cells and inflammation.
Chemical for research and analysis purposes only. Prices may vary (completely at our discretion). Not for consumption. Image is provided for reference as custom manufacturing of other related compounds is also done by us
| Product Name | Metformin |
| CAS Number | 1115-70-4 (HCl salt) ; 657-24-9 (base) |
| Synonyms | Metformin HCl; 1,1-Dimethylbiguanide hydrochloride; 3-[(Azamethyl)azamethylidenemethyl]-1,1-dimethylguanidine |
| Catalog Number | SA27506 |
| Molecular Formula | C4H12ClN5 |
| Molecular Weight | 165.62 |
| Related API | Metformin |
| Category | Impurities |