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CAS NO.6108-05-0
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factory 6108-05-0 best quality Linocaine hydrochloride supplier
Lidocaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses thereby effecting local anesthetic action. Lidocaine alters signal conduction in neurons by blocking the fast voltage gated sodium (Na+) channels in the neuronal cell membrane that are responsible for signal propagation. With sufficient blockage the membrane of the postsynaptic neuron will not depolarize and will thus fail to transmit an action potential. This creates the anaesthetic effect by not merely preventing pain signals from propagating to the brain but by aborting their birth in the first place.
A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
Catalogue Number | L397800 |
Chemical Name | Lidocaine Hydrochloride Monohydrate |
Synonyms | 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide Hydrochloride Monohydrate; Basicaina Monohydrate; Batixim Monohydrate; Dynexan Monohydrate; Heweneural Monohydrate; Licain Monohydrate; |
CAS Number | 6108-05-0 |
Alternate CAS # | 73-78-9 (anhydrous); 137-58-6 (free base) |
Molecular Formula | C??H??ClN?O? |
Appearance | White to Off-White Solid |
Melting Point | 75 - 79°C |
Molecular Weight | 288.81 |
Storage | Refrigerator |
Solubility | Chloroform (Slightly), Methanol (Slightly), Water (Slightly) |
Category | Standards; Pharmaceutical/API Drug Impurities/Metabolites; |
Applications | Anesthetic (local); antiarrhythmic (class IB). Long-acting, membrane stabilizing agent against ventricular arrhythmia. Originally developed as a local anesthetic. |