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Onchem (China) Co.,Ltd is a comprehensive manufacturer and an international distribution of chemicals throughout the world. Specialized in APIs, chemical intermediates, herbal extract and pharmaceutical raw materials.
Domperidone
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Product name |
Domperidone |
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CAS No. |
57808-66-9 |
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Molecular Structure |
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Uasage |
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EINECS: 260-968-7
Molecular Formula: C22H24ClN5O2
Synonyms: 5-Chloro-1-(1-(3-(2-oxo-1-benzimidazolinyl)propyl)-4-piperidyl)-2-benzimidazolinone; Domperidonum; Motilium;
Appearance: white powder
Molecular Weight: 425.91126
Density: 1.341 g/cm3
Melting Point: 242.5 °C
Storage Temperature: Keep tightly closed.
DMSO: >10 mg/mL
Biological Activity: Peripheral dopamine D 2 -like receptor antagonist that does not readily cross the blood brain barrier. Displays gastroprokinetic and antiemetic properties; increases the frequency and duration of antral and duodenal contractions and protects from apomorphine-induced emesis (ED 50 values are 0.003 and 0.03 mg/kg for i.v. and oral administration respectively).
Stability: Stable. Incompatible with strong oxidizing agents.
Usage: Peripheral dopamine receptor antagonist that does not cross the blood-brain barrier; anti-emetic.
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China (Mainland)