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Home>>Products>>50-78-2 best quality 50-78-2 for sale reasonable price Aspirin

50-78-2 best quality 50-78-2 for sale reasonable price Aspirin

CAS NO.50-78-2

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  • Min.Order: 25 Kilogram
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    99%(25-100.00)Kilogram

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Quick Details

  • ProName: 50-78-2 best quality 50-78-2 for sal...
  • CasNo: 50-78-2
  • Molecular Formula: C9H8O4
  • Appearance: white crystalline powder
  • DeliveryTime: 3days
  • PackAge: 25kg/drum
  • Port: Shanghai port
  • ProductionCapacity: 100000 Kilogram/Year
  • Purity: 99%min
  • Storage: Store in dry、dark、ventilated place.
  • Transportation: BY EMS,DHL,Fedex
  • LimitNum: 25 Kilogram
  • Related Substances: qualified
  • Residue on Ignition: qualifed
  • Heavy Metal: qualified
  • Valid Period: 2years
  • Batch: 20200108

Superiority

50-78-2 best quality 50-78-2 for sale reasonable price Aspirin

Aspirin is an antiinflammatory compound that inhibits NFκB, cylooxygenase-1 (Cox-1), and cyclooxygenase-2 (Cox-2). NFκB is a transcription factor that plays an important role in the expression of cellular and viral genes, which regulate the inflammatory response and infection. Adhesion molecules IL-1 and IL-6 are genes regulated by NFκB. Along with sodium salicylate (sc-3520), aspirin has been shown to block the long terminal repeat from the human immunodeficiency virus and the Ig κ enhancer from NFκB dependent transcription. Research indicates that aspirin acts at a site downstream of glutamate receptors and blocks induction of NFκB mediated by glutamate. Additional studies suggest that aspirin and sodium salicylate specifically inhibit IKKβ, which results in the blocking of NFκB genes responsible for the inflammatory response. Aspirin has also been described to elevate extracellular adenosine levels, downregulate the expression and activity of inducible NOS, decrease the levels of adenosine triphosphate, act on multiple mitogen-activated protein kinase activities, and block the uncoupling of oxidative phosphorylation. Studies reveal that aspirin alters the equilibrium of Mcl-1/Noxa, giving rise to apoptosis of leukemia cells, independent of NFκB and MAPKs.

The active ingredient in common aspirin. Incompatible with oxidizers and strong acids. Also incompatible with strong bases. May react with water or nucleophiles (e.g. amines and hydroxy groups). May also react with acetanilide, amidopyrine, phenazone, hexamine, iron salts, phenobarbitone sodium, quinine salts, potassium and sodium iodides, alkali hydroxides, carbonates, stearates and paracetanol.

Details

Catalogue Number A187780
Chemical Name Acetylsalicylic Acid
Synonyms 2-Acetoxybenzoic Acid; 2-(Acetyloxy)benzoic Acid; Acylpyrin; Angettes; Aspro; Aspirin; ASA;
CAS Number 50-78-2
Molecular Formula C?H?O?
Appearance White to Off-White Solid
Melting Point 130-132°C
Molecular Weight 180.16
Storage -20°C Freezer
Solubility DMSO (Slightly), Methanol (Slightly)
Category Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Boiling Point N/A
Applications Analgesic; antipyretic; anti-inflammatory; antithrombotic. Acetylsalicylic acid has also been shown to prevent or inhibit tumour growth, including in cervical, colorectal, lung brest, colon, pancreas, prostate and many other cancers. Aspirin is widely used as an anti-inflammatory drug. It has been shown to prevent or inhibit tumor growth, including in cervical, colorectal, lung, breast, colon, pancreas, prostate, and many other types of cancer.