Shanghai Upbio Tech Co.,Ltd（expird）
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Business Type:Lab/Research institutions
CAS NO.30123-17-2
99%(1-10000)Kilogram
Top quality 30123-17-2 good supplier 30123-17-2 Linocaine hydrochloride salt trade
Tianeptine sodium salt is a selective facilitator of 5-HT uptake in vitro and in vivo. Has no affinity for a wide range of receptors, including 5-HT and dopamine (IC50 > 10 μM) and has no effect on noradrenalin or dopamine uptake. Antidepressant, analgesic and neuroprotective following systemic administration in vivo.
Tianeptine sodium salt is a salt of Tianeptine. Tianeptine is an atypical antidepressant. It is an agonist of the μ-opioid receptor (MOR; EC50s = 194 and 641 nM for human and mouse receptors, respectively, in a BRET assay for G protein activation) and also has effects on the glutamate system. Tianeptine (30 mg/kg) decreases immobility in the forced swim test in wild-type, but not MOR knockout mice, indicating antidepressant-like activity dependent on MORs. It increases locomotor activity at a dose of 30, but not 10 mg/kg, in the open field test and increases paw withdrawal latency in the hot-plate test in mice. Tianeptine modulates AMPA receptor activity by increasing phosphorylation of the AMPA receptor GluR1 subunit in the frontal cortex and hippocampal CA3 region in mice. It prevents increases in glial glutamate transporter 1 (GLT-1) expression induced by chronic restraint stress in the hippocampal CA3 region in rats when administered at a dose of 10 mg/kg per day for 21 days.5It also reverses increases in extracellular glutamate levels induced by acute restraint stress in the basolateral nucleus of the amygdala in rats.
(1) Company Introduction:
Shanghai Upbio Tech Co.,Ltd is a comprehensive manufacturer and an international distribution of chemicals throughout the world, Specialized in APIs, chemical intermediates, herbal extract and pharmaceutical raw materials.
We have our own GMP factory with R&D centure.and cleaning workshop , and some main products produced by our own lab and R&D centure.besides we have established very good cooperation and business relations with hundreds of Chinese qualified manufacturers by long-term business intercourse.
(2) Products
| roduct name | Tianeptine sodium |
| Appearance | WHITE Powder |
| MF | C21H24ClN2NaO4S |
| Assay | 99% |
| Shelf Life | 24 months when properly stored |
| Storage | Keep in a cool, dry, dark location |
Tianeptine Sodium, also known as stablon, is a drug primarily used in the treatment of Major depressive disorder. It has also been used to treat irritable bowel syndrome and asthma. Tianeptine has antidepressant and anti-anxiety properties.
Tianeptine Sodium has a variety of effects on the body, including motivation enhancement, anxiety suppression, cognitive euphoria, focus enhancement, rejuvenation, and cognitive fatigue.
Tianeptine is antidepressant. The animal has the hippocampus pyramidal cells increased spontaneousactivity, and accelerating its function was inhibited after recovery; increase in cortical and hippocampalneurons at sites of5- serotonin reuptake. Tianeptine without following adverse effects: sleep and alertness;cardiovascular system; cholinergic system ( without anticholinergic symptoms ); drug craving
Products including:pharmaceutical raw materials, plant extract , API, and chemical intermediates. The service purpose of our company is the principle based on good faith and costumers' satisfaction.
Our products mainly developing direction is "the best quality, the best service". In recent years, with the frequently international trading, which are sold well in Europe, America, Japan, Southeast Asia, more than 40 countries and regions, with excellent quality and competitive price.
(3) Factory Picture:
Welcome to Upbio.
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