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CAS NO.163222-33-1
99%(1.00-100.00)Gram
163222-33-1 On Sale 163222-33-1 Wholesaler Ezetimibe low price
Ezetimibe, cholesterol absorption inhibitor
Potent selective cholesterol absorption inhibitor
Potent selective cholesterol absorption inhibitor. Inhibits cholesterol absorption in the intestine by preventing uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter. Ezetimibe reduces plasma cholesterol levels from 964 to 374 mg/dL, from 726 to 231 mg/dL, and from 516 to 178 mg/dL in the western, low-fat, and cholesterol-free diet mice, respectively.
> 98%
Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months
163222-33-1
| Catalogue Number | E975000 |
| Chemical Name | Ezetimibe |
| Synonyms | (3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone; Sch-58235; EZT; |
| CAS Number | 163222-33-1 |
| Molecular Formula | C??H??F?NO? |
| Appearance | White to Off-White Solid |
| Melting Point | 161 - 163°C |
| Molecular Weight | 409.43 |
| Storage | -20?C Freezer |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Category | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| Applications | An antihyperlipoproteinemic. A cholesterol absorption inhibitor. |