Keywords

• supplier 120511-73-1
• good producer 120511-73-1
• Hot Sale Anastrozole

Quick Details

• ProName: supplier 120511-73-1 good producer 120...
• CasNo: 120511-73-1
• Molecular Formula: C17H19N5
• Appearance: White powder
• Application: anastrozole has proven to be very effe...
• DeliveryTime: 3days
• PackAge: 1kg/pack,10kg/pack(Aluminum Foil Bag)
• Port: Shanghai Port
• ProductionCapacity: 1000 Kilogram/Year
• Purity: 99%min
• Storage: Store in dry,ventilated place under no...
• Transportation: By FEDEX,DHL
• LimitNum: 1 Kilogram
• Related Substances: qualified
• Residue on Ignition: qualified
• Heavy Metal: qualified
• Valid Period: 2years
• Batch: 20210409

Superiority

supplier 120511-73-1 good producer 120511-73-1 Hot Sale Anastrozole

Anastrozole, chemically known as 2,2-[5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene]bis(2-methylpropiononitrile) a derivative of benzotriazole with the CAS registry number 120511-73-1, is a non-steroidal, third-generation achiral triazole derivative marketed as ARIMIDEX® by AstraZeneca Pharmaceuticals LP1. It is one of the third-generation aromatase inhibitor which is a highly competitive and selective inhibitor of aromatase, thus blocking the conversion of testosterone into estradiol and androstenedione into estrone. Inhibition of the aromatase enzyme occurs particularly through competitive binding of aromatase to the hemegroup of cytochrome P450, decreasing estrogen biosynthesis in the peripheral tissues of the body and in the breast.

Anastrozole is a potent and highly selective aromatase (CYP19) inhibitor (IC₅₀ = 15 nM) that has no discernible effect on adrenocorticoid hormone synthesis. Reduces plasma estrogen levels and exhibits antitumor activity in vivo. Orally active.

Details