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CAS NO.1405-41-0
99%(25-1000)Kilogram
1405-41-0 factory sells 1405-41-0 Good Supplier In China Gentamycin sulfate in stock
Gentamycin sulphate is the salt form of the broad-spectrum antibiotic gentamycin (a.k.a. gentamicin). Gentamycin is active against clinically relevant bacteria, such as: Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli, Serratia marcescens, and is used to fight infections from Staphylococcus, Citrobacter and Enterobacteriaceae species. Gentamycin is a natural mixture of four congeners, one of which is gentamicin C2a. Gentamycin has been included in biomedical implantable materials, such as, bone grafts, to reduce the risk of infection.
Gentamicin is a more effective in vitro bacterial inhibitor than combined penicillin-streptomycin, is nontoxic to tissue culture monolayers, and does not inhibit virus replication. It has been used with success as an additive in commercial mycology media to inhibit growth of bacteria and has been shown to be bactericidal for a wider range of organisms (Pseudomonas aeruginosa, Proteus sp., and Streptococcus faecalis) than penicillin and streptomycin. It does not interfere with the production of cytopathic effect by certain echoviruses and polioviruses in tissue culture, is nontoxic to Rhesus monkey kidney, HeLa, and human amnion cells, and is stable at autoclave temperatures[2]. Gentamicin is produced by various species of the genus Micromonospora. Commercial gentamicin consists mainly of different gentamicin C components. Yoshizawa elucidates the 3D-structure of gentamicin C1a bound to an A-site RNA. Gentamicin C1a binds in the major groove of the A-site of the RNA
| Alternate Name | Garamycin; GM sulfate |
|---|---|
| Appearance | White to off-white solid |
| CAS # | 1405-41-0 |
| Purity | Potency: ≥590 μg/mg |
| Solubility | H?O (50 mg/ml) |
| SMILES | CC(C1CCC(C(O1)OC2C(CC(C(C2O)OC3C(C(C(CO3)(C)O)NC)O)N)N)N)NC.OS(=O)(=O)O |
| InChi | InChI=1S/C21H43N5O7.H2O4S/c1-9(25-3)13-6-5-10(22)19(31-13)32-16-11(23)7-12(24)17(14(16)27)33-20-15(28)18(26-4)21(2,29)8-30-20;1-5(2,3)4/h9-20,25-29H,5-8,22-24H2,1-4H3;(H2,1,2,3,4) |
| InChi Key | NWQISSNHRDDWRM-UHFFFAOYSA-N |
| PubChem CID | 44134730 |
| MDL Number | MFCD00270181 |
| Handling | Protect from air and moisture |
| Storage Conditions | 4°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |