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CAS NO.103-90-2
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Acetaminophen is a Cox-1, Cox-2, and Cox-3 (cyclooxygenase) inhibitor. Acetaminophen may be selective for Cox-3 (IC50 values are > 1000, > 1000, and 460 μM for murine Cox-1, murine Cox-2, and canine Cox-3, respectively). Acetaminophen is a widely used analgesic and antipyretic agent.
Obtain prism crystallization from ethanol. Melting point 169-171℃, relative density 1.293(21/4℃). Soluble in ethanol, acetone and hot water, difficult to dissolve in water, insoluble in petroleum ether and benzene. Odorless, bitter. The pH value of saturated aqueous solution is 5.5-6.5.
Acetaminophen is a cyclooxygenase inhibitor; may be selective for COX-3 (IC50 values are 460, > 1000 and > 1000 μM for canine COX-3, and murine COX-1 and COX-2 respectively). Widely used analgesic and antipyretic agent.
Catalogue Number | A161220 |
Chemical Name | Acetaminophen |
Synonyms | N-(4-Hydroxyphenyl)acetamide; 4’-Hydroxyacetanilide; 4-Acetamidophenol; N-Acetyl-4-aminophenol; APAP; Acamol; Acenol; Paracetamol; Paracetamole; Parageniol; Paralen; Paramol; Paraspen; Valadol; Valgesic; Vermidon; |
CAS Number | 103-90-2 |
Molecular Formula | C?H?NO? |
Appearance | White to Off-White Solid |
Melting Point | 167-1700C |
Molecular Weight | 151.16 |
Storage | Room Temp |
Solubility | DMSO (Sparingly), Methanol (Slightly) |
Category | Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites; |
Boiling Point | N/A |
Applications | Acetaminophen is analgesic and antipyretic drug. It is a pain reliever commonly used to treat headache, muscle aches, arthritis, and other acute or chronic painful conditions.This compound is a contaminant of emerging concern (CECs). |